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Publications

Feiner R.C., Müller K.M., "Recent progress in protein-protein interaction study for EGFR-targeted therapeutics." Expert Rev Proteomics., Jul 29:1-16, 2016.

Hagen S., Baumann T., Wagner H.J., Morath V., Kaufmann B., Fischer A., Bergmann S., Schindler P, Arndt K.M., Müller K.M. “Modular adeno-associated virus (rAAV) vectors used for cellular virus-directed enzyme prodrug therapy”. Sci. Rep.,4:3759, 2014.

Kükenshöner T., Hagemann U.B., Wohlwend D., Räuber C., Baumann T., Keller S., Einsle O., Müller K.M., Arndt K.M. “Analysis of selected and designed chimeric D- and L-α-helix assemblies.“ Biomacromolecules, 15(9):3296-305, 2014.

Hagen S., Mattay D., Räuber C., Müller K.M., Arndt K.M. “Characterization and inhibition of AF10-mediated interaction.” J. Pept. Sci. 20(6):385-97, 2014. 

Weiz A.R., Ishida K., Quitterer F., Meyer S., Kehr J.C., Müller K.M., Groll M., Hertweck C., Dittmann E., "Harnessing the evolvability of tricyclic microviridins to dissect protease-inhibitor interactions.", Angew Chem Int Ed Engl. 53(14):3735-8, 2014.

Kükenshöner T., Wohlwend D., Niemöller C., Dondapati P., Speck J., Adeniran A.V., Nieth A., Gerhardt S., Einsle O., Müller K.M., Arndt K.M. “Improving coiled coil stability while maintaining specificity by a bacterial hitchhiker selection system.” J. Struct. Biol., 186(3):335-48, 2014.

Baumann T., Arndt K.M., Müller K.M. “Directional cloning of DNA fragments using deoxyinosine-containing oligonucleotides and endonuclease V”. BMC Biotechnol., 13(1):81, 2013.

Jedrusik-Bode M., Studencka M., Smolka C., Baumann T., Schmidt H., Kampf J., Paap F., Martin S., Tazi J., Müller K.M., Krüger M., Braun T., Bober E. “The sirtuin SIRT6 regulates stress granules formation in C. elegans and in mammals.”; J. Cell Sci., 126(Pt 22):5166-77, 2013.

Speck J, Räuber C., Kükenshöner T., Niemöller C., Mueller K. J., Schleberger P., Dondapati P., Hecky J., Arndt K. M., Müller K.M. ”TAT Hitchhiker selection expanded to folding helpers, multimeric interactions, and combinations with protein fragment complementation” Prot. Eng. Des. Sel., Mar., 26(3):225-42, 2013

Klingström T., Soldatova L., Stevens R., Roos T.E., Swertz M.A., Müller K.M., Kalaš M., Lambrix P., Taussig M.J., Litton J.E., Landegren U., Bongcam-Rudloff E. “Workshop on laboratory protocol standards for the molecular methods database”. N. Biotechnol., Jan 25, 30(2):109-13, 2013.

Speck J., Hecky J., Tam H.-K., Arndt K.M., Einsle O., Müller K.M. “Exploring Molecular Linkage of Protein Stability Traits for Enzyme Optimization by Iterative Truncation and Evolution”, Biochemistry, 51, 4850−4867, 2012

Müller K.M., Arndt K. M. „iGEM und BioBricks – internationaler Wettbewerb zur Synthetischen Biologie“ Biospektrum, 01.12, 106-107, 2012.

Müller K.M., Arndt KM. “Standardization in synthetic biology”. Methods in Molecular Biology 813, 23-43, 2012.

Zhang F, Müller K.M., Woolley G. A., Arndt K.M. “Light-controlled gene switches in mammalian cells”. Methods in Molecular Biology 813, 813:195-210, 2012.

Speck, J., Arndt, K.M., Müller, K.M. “Efficient phage display of intracellularly folded proteins mediated by the TAT pathway”. Prot. Eng. Des. Sel. 24(6), 473-484, 2011.

Staab, P.R., Walossek, J., Nellessen, D., Grünberg, R., Arndt, K.M., Müller, K.M. “SynBioWave-a real-time communication platform for molecular and synthetic biology”. Bioinformatics 26 (21), 2782-2783, 2010.

Schäffer U., Schlosser A., Müller K.M., Schäfer A., Katava N., Baumeister R., Schulze E., “ SnAvi--a new tandem tag for high-affinity protein-complex purification”. Nucleic Acids Res., 38(6):e91, 2010.

Gaisser S., Reiss T., Lunkes A., Müller K.M., Bernauer H. “Making the most of synthetic biology”, EMBO Rep., Suppl. 1:S5-8, 2009.

Gaida A., Hagemann U.B., Mattay D., Räuber C., Müller K.M., Arndt K.M. “Selection of peptides interfering with protein-protein interaction”. Methods Molecular Biology 535, 263-91, 2009.

Mason, J.M., Müller, K.M., Arndt, K.M. “Peptides Tailored to Interfere with Protein Interaction and Function”. Chemistry Today 27(2): 47-50, 2009.

Mason, J.M., Müller, K.M. & Arndt, K.M. “iPEP: peptides desigend and selected for interfering with protein interaction and function”. Biochem Soc Trans. 36(6): 1442-1447, 2008.

Müller O., Arndt K.M., Müller K.M., Boldt J. “Von der Manipulation zur Kreation - Ethische und ontologische Aspekte der synthetischen Biologie“. Jahrbuch für Wissenschaft und Ethik, De Gruyter, Berlin, New York, Vol. 13, 153-180, 2008.

Jouaux, E.M., Schmidtkunz, K., Müller, K.M. & Arndt, K.M. “Targeting the c-Myc coiled coil with interfering peptides to inhibit DNA binding.” J. Pept. Sci., 14(9):1022-1031, 2008.

Stebel S.C., Gaida A., Arndt, K.M., Müller K.M. “Directed Protein Evolution”, Molecular Biomethods Handbook 2nd ed., Humana Press / Springer Science, 587-629, 2008.

Willemsen T, Hagemann, U.B., Jouaux, E.M., Stebel, S.C., Mason, J.M., Müller, K.M., Arndt, K.M. “Protein Engineering”, Molecular Biomethods Handbook, 2nd ed., Humana Press / Springer Science 587-629, 2008.

Hagemann, U.B., Mason, J.M., Müller, K.M. & Arndt, K.M. “Selectional and mutational scope of peptides sequestering the c-Fos coiled coil domain.” Journal of Molecular Biology, 381, 1, 73-88, 2008.

Mason, J.M., Müller, K.M., Arndt, K.M. “Positive Aspects of Negative Design: Simultaneous Selection of Specificity and Stability”, Biochemistry, 46, 4804-4814, 2007.

Hecky, J., Mason, J.M., Arndt, K.M., Müller, K.M. "A general method of terminal truncation, evolution and re-elongation to generate enzymes of enhanced stability" Methods in Molecular Biology, 352, 275-304, 2007.

Stebel, S.C., Arndt, K.M., Müller, K.M. "Versatile DNA fragmentation and directed evolution with Nucleotide Exchange and Excision Technology (NExT)" Methods in Molecular Biology, 352, 167-90, 2007.

Mason, J.M., Müller, K.M., Arndt, K.M. "Considerations in the Design and Optimization of Coiled coil Structures." Methods in Molecular Biology, 352, 35-70, 2007.

Mason, J.M., Schmitz, M.A., Müller, K.M. & Arndt, K.M. “Semi-rationally Designed Jun-Fos Coiled Coils with Increased Affinity: Universal Implications in Leucine Zipper Design and Prediction” Proceedings of the National Academy of Science U.S.A., 103, 8989-8994, 2006.

Hecky J., Müller K.M. “Structural Perturbation and Compensation by Directed Evolution at Physiological Temperature Leads to Thermostabilization of beta-Lactamase”. Biochemistry, 44, 12640-12654, 2005.

Müller K.M.*, Stebel S.C., Knall S., Zipf G., Bernauer H.S., Arndt K.M. "Nucleotide exchange and excision technology (NExT) DNA shuffling: a robust method for DNA fragmentation and directed evolution". Nucleic Acids Research, 33, e117, 2005.

* corresponding author

Köhler F., Müller K.M. "Adaptation of the Ras-recruitment system to the analysis of interactions between membrane-associated proteins". Nucleic Acids Research, 31, e28, 2003.

Arndt, K.M., Pelletier, J.N., Müller, K.M., Plückthun, A., Alber, T. "Comparison of in-vivo Selection and Rational Design of Heterodimeric Coiled Coils". Structure, 10, 1235-1248, 2002.

Arndt, K.M., Müller, K.M., Plückthun, A. "Helix-stabilized Fv (hsFv) Antibody Fragments: Substituting the Constant Domains of a Fab Fragment for a Heterodimeric Coiled-coil Domain". Journal of Molecular Biology 312, 221-228, 2001.

Arndt, K.M., Müller, K.M., Pelletier, J.N. & Plückthun, A. “Heteroassociating coiled-coil peptides and screening method therefore”. Patent CA 2,377,513; EP1194539; WO 01/00814; 2001

Arndt, K.M., Pelletier, J.N., Müller, K.M., Alber, T., Michnick, S.W., Plückthun, A.; “A Heterodimeric Coiled-Coil Peptide Pair Selected in vivo from a Designed Library-versus-Library Ensemble”. Journal of Molecular Biology, 295, 627-639, 2000.

Müller, K.M., Arndt, K.M., Alber, T.; “Protein Fusions to Coiled Coil Domains”. Methods in Enzymology, “Chimeric Genes and Proteins”, Eds. J. Abelson and M.I. Simon, 328, 364-388, 2000.

Jung S., Arndt, K.M., Müller, K.M., Plückthun A., “Selectively-infective phage (SIP) Selection technology: scope and limitation”. Journal of Immunological Methods, 231, 93-104, 1999.

Müller, K.M., Arndt, K.M., Plückthun, A.; “Model and Simulation of Multivalent Binding to Fixed Ligands”. Analytical Biochemistry, 259, 54-61, 1998.

Arndt, K.M., Müller, K.M., Plückthun, A.; “Factors Influencing the Dimer to Monomer Transition of an Antibody Single-Chain Fv Fragment”. Biochemistry, 37, 12918-12926, 1998.

Müller, K.M., Arndt, K.M., Plückthun, A.; “A Dimeric Bispecific Miniantibody Combines Two Specificities with Avidity”. FEBS Letters, 432, 45-49, 1998.

Müller, K.M., Arndt, K.M., Bauer, K., Plückthun, A.; “Tandem Immobilized Metal-Ion Affinity Chromatography / Immunoaffinity Purification of His-tagged Proteins - Evaluation of Two Anti-His-Tag Monoclonal Antibodies”. Analytical Biochemistry, 259, 54-61, 1998.

Müller, K.M., Arndt, K.M., Strittmatter, W., Plückthun, A.; “The first Constant Domain (CH1 and CL) of an Antibody used as Heterodimerization Domain for Bispecific Miniantibodies”. FEBS Letters, 422, 259-264, 1998.

Horn, U., Strittmatter, W., Krebber, A., Knüpfer, U., Kujau, M., Wenderoth, R., Müller, K., Matzku, S., Plückthun, A., Riesenberg, D.; “High volumetric yields of functional dimeric miniantibodies in Escherichia coli, using an optimized expression vector and high-cell-density fermentation under non-limited growth conditions”. Applied Microbiology and Biotechnology, 46, 524-532, 1996.

Müller, K.M., Gempeler, M.R., Scheiwe, M.-W., Zeugin, B.T.; “Quality Assurance for Biopharmaceuticals: An Overview of Regulations, Methods and Problems”. Pharmaceutica Acta Helvetiae, 71, 421-438, 1996.

Pack, P., Müller, K., Zahn, R., Plückthun, A.; “Tetravalent Miniantibodies with High Avidity Assembling in Escherichia coli”. Journal of Molecular Biology, 256, 28-34, 1995.

Bahar, L. O. Essen, J. Moult, K.M. Müller; “Design of a Heterodimer from a Homotetramer: SILKY ; BIOcomputing Technical Document 8, European Molecular Laboratory, 1994

Müller, K.M., Ebensperger, C., Tampé, R.; “Nucleotide Binding to the Hydrophilic C-terminal Domain of the Transporter Associated with Antigen Processing (TAP)”. Journal of Biological Chemistry, 269(19), 14032-14037, 1994.


ADDRESS
Kristian M. Müller
Room UHG E2-143
Universitätsstr. 25
33615 Bielefeld
Germany

CONTACTS
Tel. +49-521-106-6323 (office)
Tel. +49-521-106-6318 (secretary)
Fax. +49-521-106-156318
e-mail kristian@syntbio.net
http://www.syntbio.net